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Holiday Inn Express & Suites Hannibal - Medical Center

4.8(574)
Hotel

About

Holiday Inn Express & Suites Hannibal - Medical Center offers modern, well-lit rooms with thoughtful amenities like Keurig coffee makers, microwaves, and irons, designed for comfortable overnight stays. The hotel’s location just off the highway ensures easy access without traffic noise intrusion.

Business travelers can take advantage of the indoor pool and fitness center to unwind or stay active, while the spacious breakfast area serves a wide selection of freshly brewed coffee and hot options. Its clean, contemporary setting and friendly staff provide a straightforward, reliable experience for small group stays or multi-night bookings.

Best for

  • Multi-night group stays with modern amenities
  • Team lodging near highway access
  • Casual business travel with breakfast included

Request a Package

Tell the venue what you're planning and they'll respond with a custom proposal within 1–2 business days.

Group Meeting

Custom request

Professional meeting space for your team — whether it's a meeting, training, workshop, or multi-day offsite. Half-day, full-day, or multi-day — with the option to request AV, catering, and your preferred room layout.

What's typically included

  • Meeting room & layout
  • Food & beverage
  • AV & technology

Room Block

Custom request

Reserve a block of rooms for your group — ideal for multi-day conferences, offsites, or any event where attendees are traveling from out of town.

What's typically included

  • Reserved guest rooms for your group
  • Flexible check-in & check-out dates
  • Negotiated group rates

Meeting + Room Block

Custom request

Bundle your meeting space and guest rooms in one request — perfect for multi-day offsites and conferences where the team meets by day and stays overnight.

What's typically included

  • Meeting room & layout
  • Food & beverage
  • AV & technology
  • Reserved guest rooms for your group

Venue Details

Standout features

Clean, gently warm indoor pool
Indoor Amenities
Clean, gently warm indoor pool
A well-maintained indoor pool that guests find comfortable and refreshing, offering a pleasant option for relaxation or light exercise during events.
Bright, spacious rooms with thoughtful touches
Guest Comfort
Bright, spacious rooms with thoughtful touches
Rooms are noted for being spacious and well-lit, with comfortable beds and pillow options, plus amenities like irons, microwaves, and Keurig coffee makers to enhance guest convenience.
Generous breakfast with fresh coffee and buffet variety
Breakfast Experience
Generous breakfast with fresh coffee and buffet variety
A standout breakfast featuring freshly ground and brewed coffee, a pancake machine, and a large selection of buffet items, with attentive staff ensuring guests have ample time to enjoy the meal.

At a glance

Rated 4.8 on Google · 574 reviews