21c Museum Hotel Lexington
4.4(1,399)
Hotel
About
21c Museum Hotel Lexington offers a blend of contemporary art and boutique comfort in downtown Lexington's historic Fayette National Bank building. Its thoughtfully designed rooms feature spacious layouts, Nespresso machines, and work-friendly tables, making it ideal for productive stays and small meetings.
The hotel provides private event spaces infused with cultural flair, perfect for corporate gatherings and receptions. Located on Main Street, it offers easy access to local business hubs and attractions like Keeneland Race Course and the Kentucky Bourbon Trail, with valet parking and in-room dining enhancing convenience.
Best for
- Boutique downtown hotel stays with artful ambiance
- Private events & corporate receptions
- In-room dining & focused work sessions
Standout features
Architecture & Art
Museum hotel in a historic 1914 bank building
The hotel transforms the former Fayette National Bank into a contemporary art-filled space with immersive installations like the Nightwatch Artist Suite and the Spectralline entry by SOFTLab, blending history with modern design.
Location
Downtown Lexington on Main Street
Centrally located in the heart of Lexington, the hotel offers easy access to local attractions like Keeneland Race Course and the Kentucky Bourbon Trail, making it convenient for business travelers and event guests.
In-Room Amenities
Well-appointed rooms with workspace and Nespresso bar
Rooms feature comfortable beds, spacious layouts with sofas, dedicated work tables, and in-room coffee bars equipped with Nespresso machines, supporting both relaxation and productivity.
At a glance
Location & hours
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Rated 4.4 on Google · 1,399 reviews